This article documents the different forms of advocacy and highlights the importance of advocacy in the UK health- and social-care settings. It draws on a number of elements related to advocacy to demonstrate the challenges that nurses may encounter. Moreover, it identifies the skills and knowledge that nurses may use as being advocates for patients/clients and their families. The article makes a strong argument by highlighting that nurses are essential advocates and are duty-bound to adhere to their professional code of conduct. The Nursing and Midwifery Council (NMC) Code clearly states that nurses must ensure that patients/clients and their families are protected, respected, treated with dignity, and are given the highest standard of person-centered care. This article has considered these in relation to nurse advocacy.